New Laser Capture Microdissection (LMD) Microscope

1.1.

Køber

Officielt navn : Danmarks Tekniske Universitet - DTU

E-mail : mardau@dtu.dk

Køberens retlige status : Offentligretligt organ

Den ordregivende myndigheds aktiviteter : Uddannelse

2.1.

Procedure

Titel : New Laser Capture Microdissection (LMD) Microscope

Beskrivelse : DTU Bioengineering is looking to acquire a Laser capture MicroDissection (LMD) system to enable their ambitions in the field of spatial proteomics, transcriptomics, and multi-omics, all the way down to single-cell level. The main ambition is to expand their analytical capabilities and consoli-dating its internationally leading position in the field of single-cell proteomics by Mass Spectrometry (scp-MS). The instrument will be used for running large-scale spatial scp-MS experiments, de-veloping novel microfluidic platform supported sample preparation workflows, implementing single-cell multi-omics experimental workflows and supporting spatial single-cell RNA sequencing experiments.

Identifikator for proceduren : 6f9b0ce8-7fe7-470a-ba4a-d9fa9de249d6

Intern identifikator : 9254

Udbudsprocedure : Udbud med forhandling uden forudgående offentliggørelse

2.1.1.

Formål

Kontraktens art : Varer

Primær klassificering ( cpv ): 38430000 Apparater til fysisk eller kemisk analyse

Yderligere klassificering ( cpv ): 73120000 Eksperimentel udvikling

2.1.2.

Udførelsessted

By : Kgs. Lyngby

Postnummer : 2800

Landespecifik underafdeling (NUTS) : Københavns omegn ( DK012 )

Land : Danmark

2.1.4.

Generelle oplysninger

Retsgrundlag :

Direktiv 2014/24/EU

5.1.

Delkontrakt : LOT-0000

Titel : New Laser Capture Microdissection (LMD) Microscope

Beskrivelse : DTU Bioengineering is looking to acquire a Laser capture MicroDissection (LMD) system to enable their ambitions in the field of spatial proteomics, transcriptomics, and multi-omics, all the way down to single-cell level. The main ambition is to expand their analytical capabilities and consoli-dating its internationally leading position in the field of single-cell proteomics by Mass Spectrometry (scp-MS). The instrument will be used for running large-scale spatial scp-MS experiments, de-veloping novel microfluidic platform supported sample preparation workflows, implementing single-cell multi-omics experimental workflows and supporting spatial single-cell RNA sequencing experiments.

Intern identifikator : 9254

5.1.1.

Formål

Kontraktens art : Varer

Primær klassificering ( cpv ): 38430000 Apparater til fysisk eller kemisk analyse

Yderligere klassificering ( cpv ): 73120000 Eksperimentel udvikling

5.1.2.

Udførelsessted

By : Kgs. Lyngby

Postnummer : 2800

Landespecifik underafdeling (NUTS) : Københavns omegn ( DK012 )

Land : Danmark

5.1.3.

Anslået varighed

Startdato : 31/08/2024

Varigheds slutdato : 31/08/2034

5.1.6.

Generelle oplysninger

Indkøbsprojekt, der ikke finansieres med EU-midler

Udbuddet er omfattet af aftalen om offentlige udbud (GPA) : ja

5.1.10.

Tildelingskriterier

Kriterium :

Type : Pris

Navn : Price

Beskrivelse : According to offer from supplier.

Vægtning (procentdel, præcis) : 100

5.1.12.

Udbudsvilkår

Oplysninger om undersøgelsesfrister : Complaint that the Contracting Authority, contrary to the Public Procurement Act, has concluded a contract without prior publication of a contract notice in the European Union Official Journal must be submitted no later than 30 calendar days from the date after a contract award notice has been published by the Contracting Authority in the European Union Official Journal and that contract award notice includes the grounds for the decision to award the contract directly, cf. lov om Klagenævnet for Udbud (Complaints Board for Tenders) § 7, section 3.

5.1.15.

Teknikker

Rammeaftale : Ingen rammeaftale

Oplysninger om det dynamiske indkøbssystem : Intet dynamisk indkøbssystem

5.1.16.

Yderligere oplysninger, mægling og gennemgang

Organisation med ansvar for klager : Klagenævnet for Udbud

Organisation, der leverer oplysninger om den generelle lovgivningsramme på det sted, hvor kontrakten skal udføres, hvad angår skatter : Konkurrence- og Forbrugerstyrelsen

Organisation, der leverer supplerende oplysninger om udbudsproceduren : Danmarks Tekniske Universitet - DTU

Organisation, der sikrer adgang til udbudsdokumenterne offline : Danmarks Tekniske Universitet - DTU

Organisation, hvis budget anvendes til at betale for kontrakten : Danmarks Tekniske Universitet - DTU

Organisation, der udfører betalingen : Danmarks Tekniske Universitet - DTU

Organisation, der undertegner kontrakten : Danmarks Tekniske Universitet - DTU

TED eSender : Mercell Holding ASA

Værdien af alle kontrakter tildelt i denne meddelelse : 1 600 122,24 DKK

Direkte tildeling :

Begrundelse for direkte tildeling : Kontrakten kan kun tildeles af en bestemt økonomisk aktør på grund af manglende konkurrence af tekniske årsager

Anden begrundelse : DTU Bioengineering is looking to acquire a Laser capture MicroDissection (LMD) system to enable their ambitions in the field of spatial proteomics, transcriptomics, and multi-omics, all the way down to single-cell level. The main ambition is to expand their analytical capabilities and consolidating its internationally leading position in the field of single-cell proteomics by Mass Spectrometry (scp-MS). The instrument will be used for running large-scale spatial scp-MS experiments, developing novel microfluidic platform supported sample preparation workflows, implementing single-cell multi-omics experimental workflows and supporting spatial single-cell RNA sequencing experiments. Recognizing, and isolating, specific single-cells from primary samples requires a unique combination of fluorescent microscopy with high-resolution lasers and appropriate sample collection devices. The LMD6 laser microdissection system is distributed by Leica Microsystems and is the only LMD system on the market that is designed, developed, and manufactured by a single company, encompassing all the required features. This allows DTU to have a single point of contact for both the application of hardware / software development, and for the technical support service. Leica Microsystems applies the most delicate technique for specimen collection: gravity. Gravity is the most sensible method of specimen collection as no additional force is required. Most importantly, the specimens are not touched. This makes specimen collection by gravity a contamination-free procedure. Importantly, Leica is the sole manufacturer of LMD systems that allow contactless collection into 384-well PCR plates, which is essential for our experimental workflows, relying on low-volume, contamination-free sample preparation. Moreover, Leica is the only manufacturer with es-tablished Artificial Intelligence (AI) supported automated cell recognition, to ensure the highest throughput, combined with correct cell isolation for follow-up analysis. Hence, the LMD6 is the only instrument available on the market that will enable us to achieve our goals in the context of low-input, contamination-free, and high-throughput sample preparation for LC-MS based proteomics from e.g. FFPE clinical specimens or fresh-frozen material. Other justification: There is lack of competition due to technical reasons, cf. § 80, subsection 3, no. 2 in the Danish Public Procurement Law. The contract is awarded to Leica Microsystems, as their LMD6 product is the only instrument on the market that can fulfil all our requirements, in a single instrument platform, with a single point of contact for 1) single-cell isolation, 2) collection of isolated specimens into 384-well plates and other specific vessels (e.g. ProteoChip Evo as commercially available from Cellenion), 3) collection of isolated specimens by means of gravity, and 4) Artificial Intelligence (AI) supported automated cell recognition. Detailed features of the LMD6 and why this is a unique instrument has been provided above. A market survey was conducted to explore all possible options for a single instrument dedicated for spatial isolation of single cells by means of LMD, for subsequent proteomic and transcriptomic analysis. We have explored different suppliers, but none of them offer a single-instrument option, with commercially available consumables and software for automated cell recognition and isolation, at single-cell resolution. Other instruments either 1) require laser propulsion of isolated specimens, thereby possibly damaging the tissue in the process, 2) do not allow for collection of specimens into 384-well plates, required for low-volume, automated sample preparation, or 3) do not have AI-supported cell recognition abilities to automate the isolation process. Combined, this means that using alternative suppliers would result in our inability to obtain sufficient data quality for our biological experiments. This makes the Leica LMD6 the only instrument currently on the market that provides a solution for our high-sensitivity and high-throughput experimental spatial proteomics and transcriptomics workflow demands.

6.1.

Resultat delkontrakt-ID : LOT-0000

6.1.2.

Oplysninger om vinderne

Vinder :

Officielt navn : Leica Microsystems A/S

Tilbud :

Tilbud – Identifikator : 9254

Identifikator for delkontrakt eller gruppe af delkontrakter : LOT-0000

Kontraktoplysninger:

Identifikator for kontrakten : 373744

Titel : New Laser Capture Microdissection (LMD) Microscope

Datoen for udvælgelsen af det vindende tilbud : 16/08/2024

Kontrakten tildeles som led i en rammeaftale : nej

Organisation, der undertegner kontrakten : Danmarks Tekniske Universitet - DTU

8.1.

ORG-0001

Officielt navn : Danmarks Tekniske Universitet - DTU

Registreringsnummer : 30060946

Postadresse : Anker Engelunds Vej 1

By : Kgs. Lyngby

Postnummer : 2800

Landespecifik underafdeling (NUTS) : Københavns omegn ( DK012 )

Land : Danmark

Kontaktpunkt : Marianne Dauding

E-mail : mardau@dtu.dk

Telefon : +45 33344398

Internetadresse : https://www.dtu.dk

Køberprofil : https://eu.eu-supply.com/ctm/company/companyinformation/index/165863

Denne organisations roller :

Køber

Organisation, der leverer supplerende oplysninger om udbudsproceduren

Organisation, der sikrer adgang til udbudsdokumenterne offline

Organisation, der undertegner kontrakten

Organisation, hvis budget anvendes til at betale for kontrakten

Organisation, der udfører betalingen

8.1.

ORG-0002

Officielt navn : Klagenævnet for Udbud

Postadresse : Nævnenes hus, Toldboden 2

By : Viborg

Postnummer : 8800

Landespecifik underafdeling (NUTS) : Østjylland ( DK042 )

Land : Danmark

E-mail : klfu@erst.dk

Telefon : +45 35291000

Denne organisations roller :

Organisation med ansvar for klager

8.1.

ORG-0003

Officielt navn : Konkurrence- og Forbrugerstyrelsen

Postadresse : Carl Jacobsens Vej 35

By : Valby

Postnummer : 2500

Landespecifik underafdeling (NUTS) : Byen København ( DK011 )

Land : Danmark

E-mail : kfst@kfst.dk

Telefon : +45 41715000

Denne organisations roller :

Organisation, der leverer oplysninger om den generelle lovgivningsramme på det sted, hvor kontrakten skal udføres, hvad angår skatter

8.1.

ORG-0004

Officielt navn : Leica Microsystems A/S

By : Brønshøj

Postnummer : 2700

Landespecifik underafdeling (NUTS) : Københavns omegn ( DK012 )

Land : Danmark

E-mail : manie@triolab.dk

Telefon : +4544540101

Denne organisations roller :

Tilbudsgiver

Vinder af disse delkontrakter : LOT-0000

8.1.

ORG-0005

Officielt navn : Mercell Holding ASA

Registreringsnummer : 980921565

Postadresse : Askekroken 11

By : Oslo

Postnummer : 0277

Landespecifik underafdeling (NUTS) : Oslo ( NO081 )

Land : Norge

Kontaktpunkt : eSender

E-mail : publication@mercell.com

Telefon : +47 21018800

Fax : +47 21018801

Internetadresse : http://mercell.com/

Denne organisations roller :

TED eSender

11.1.

Oplysninger om bekendtgørelsen

Identifikator for bekendtgørelsen : b28c22a4-0eeb-4da0-b0f8-94a283b08b72 - 01

Formulartype : Forudgående underretning om direkte tildeling

Bekendtgørelsestype : Bekendtgørelse med henblik på frivillig forudgående gennemsigtighed

Bekendtgørelsessubtype : 25

Afsendelsesdato for bekendtgørelsen : 19/08/2024 14:57:19 (UTC)

Dato for afsendelse af bekendtgørelse (eSender) : 19/08/2024 18:56:36 (UTC)

Sprog, som denne bekendtgørelse er officielt tilgængelig på : dansk

11.2.

Oplysninger om offentliggørelsen

Bekendtgørelsesnummer : 502147-2024

EUT-S-nummer : 162/2024

Offentliggørelsesdato : 21/08/2024

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New Laser Capture Microdissection (LMD) Microscope

Danmarks Tekniske Universitet - DTU

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